Anglia Ruskin Centre for Circulatory Health

The Cardiology Research Unit is a collaboration with the Essex Cardiothoracic Centre (ECTC) at Basildon and Thurrock University Hospitals NHS Foundation Trust, Essex.

The combined expertise makes the setting up and running of cardiovascular (heart and lung) and thoracic (chest) clinical trials more efficient and effective, benefiting clinicians and researchers as well as present and future patients. ECTC provides tertiary cardiac services for a population of approximately 1.7 million people.

Research projects are wide ranging and include non-interventional (electrophysiology and imaging) and interventional cardiology. The joint research unit has particular expertise in trialling cardiology medical devices.

The ECTC has some of the country’s most modern cardiothoracic treatment facilities. Clinicians are involved in research programmes across anaesthetics, cardiac physiology, cardiac and thoracic surgery, interventional cardiology and perfusion.

Javanbakht, M., Mashayekhi, A., Hemami, M. R., Branagan-Harris, M., Keeble, T. R., Yaghoubi, M., 2022. Cost-Effectiveness Analysis of Intravascular Targeted Temperature Management after Cardiac Arrest in England. PharmacoEconomics - Open, May 3. Online ahead of print. doi: 10.1007/s41669-022-00333-7. PMID: 35503202

Karamasis, G. V., Khan, S., Alsanjari, O., Davies, J. R., Keeble, T. R., 2022. Coronary flow autoregulation during Impella CP support post successful chronic total occlusion percutaneous coronary intervention. Coron Artery Dis., Apr 28. Online ahead of print. doi: 10.1097/MCA.0000000000001150. PMID: 35500097

Dunning, J., Archbold, A., de Bono, J. P., Butterfield, L., Curzen, N., Deakin, C. D., Gudde, E., Keeble, T. R., Keys, A., Lewis, M., O'Keeffe N., Sarma, J., Stout, M., Swindell, P., Ray, S., 2022. Joint British Societies' guideline on management of cardiac arrest in the cardiac catheter laboratory. Heart, Apr 25. Online ahead of print. doi: 10.1136/heartjnl-2021-320588. PMID: 35470236

Mion, M., Magee, N., Davis, J., Farrell, K., Nikolopoulou, E., Jessup, D., Davies, J., Karamasis, G., Keeble, T., 2022. Exploring cognitive impairment in the early stages of an out-of-hospital cardiac arrest – a consecutive case series study. Neuropsychol Rehabil, Mar 28, pp. 1-18. Online ahead of print. doi: 10.1080/09602011.2022.2052325

Konstantinou, K., Davies, J. R., Alsanjari, O., Kelly, P. A., Tang, K. H., Kassimis, G., Alexopoulos, D., Clesham, G. J., Keeble, T. R., Karamasis, G. V., 2022. Clinical effectiveness of thrombus aspiration during percutaneous coronary intervention for stent thrombosis in a contemporary setting, Hellenic J Cardiol, Mar 16, S1109-9666(22)00030-6. Online ahead of print. doi: 10.1016/j.hjc.2022.03.004. PMID: 35304315

Nowbar, A. N., Rajkumar, C., Foley, M., Ahmed-Jushuf, F., Howard, J. P., Seligman, H., Petraco, R., Sen, S., Nijjer, S. S., Shun-Shin, M .J., Keeble, T. R., Sohaib, A., Collier, D., McVeigh, P., Harrell, F. E., Francis D. P., Al-Lamee, R. K., 2022. A double-blind randomised placebo-controlled trial of percutaneous coronary intervention for the relief of stable angina without antianginal medications: design and rationale of the ORBITA-2 trial. EuroIntervention, 17(18), pp. 1490-1497. doi: 10.4244/EIJ-D-21-00649. PMID: 35156616

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