Dr Jasmine Samvelyan

Dr Jasmine Samvelyan is a Senior Lecturer in Biomedical Science for the MBChB course and Lead of the Musculoskeletal and Developmental Biology Research Group, part of ARU's Medical Technology Research Centre (MTRC). Her expertise lies in utilizing cellular, molecular and in vivo approaches to study musculoskeletal ageing.

[email protected]

Follow Dr Samvelyan on Twitter @JSamvelyan

View Dr Samvelyan's ORCID profile (0000-0001-9576-8001)

Background

Dr Samvelyan completed a BSc (honours) degree in Biomedical Science with Sheffield Graduate Award at The University of Sheffield. Before pursuing a PhD at the Medical Research Council - Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing (CIMA) at The University of Sheffield, Newcastle University and University of Liverpool, Dr Samvelyan was awarded a Master of Research (MRes, Distinction) in Musculoskeletal Ageing at the CIMA. In this innovative graduate training programme, she studied the effects of ageing on musculoskeletal system to identify interventions that reduce deleterious effects of ageing on the skeleton.

Her doctoral studies were focused on the area of interactions of hormonal and mechanical stimuli on the skeleton, a subject with the relevance and potential impact on bone pathologies including osteoporosis and osteopenia. Dr Samvelyan was awarded for a postgraduate internship at the Department of Genetics, Boston Children's Hospital of Harvard Medical School.

Dr Samvelyan was then awarded a Medical Research Council funded research fellowship in osteoarthritis at University of Brighton. She lectured and led Student-Selected Components (SSCs) of Years 1-2 medical students (BM BS) at Brighton and Sussex Medical School, before joining Anglia Ruskin University School of Medicine as a lecturer in Biomedical Science. Dr Samvelyan attained Postgraduate Certificate in Learning, Teaching and Assessment Practice in Higher Education accredited by the Staff and Educational Development Association (SEDA).

Dr Samvelyan leads the Musculoskeletal and Developmental Biology Research Group, which brings together a wealth of expertise in practical innovation, state-of-the-art facilities, and medical technologies. The group applies learning from research aimed to transform understanding of development, ageing and age-related disease aetiopathogenesis into clinical practice and real-life context.

Dr Samvelyan was invited to Her Majesty’s Garden Party at Buckingham Palace for her continued volunteering work at the NHS and community activities.

Research interests

• Endocrinology
• Musculoskeletal Ageing
• Osteoarthritis
• Physical activity and energy metabolism

Areas of research supervision

Dr Samvelyan supervises research projects of both undergraduate and postgraduate Master's and doctoral students. She embraces student-centred, research-based and enhancement-led constructivist approach to learning, teaching and assessment practice. 

Teaching

• MBChB
• MSc

Qualifications

• Postgraduate Certificate in Learning, Teaching and Assessment Practice in Higher Education accredited by the Staff and Educational Development Association (SEDA), Edinburgh Napier University, 2020
• PhD Musculoskeletal Ageing, The MRC – Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing (CIMA), The University of Sheffield, Newcastle University, 2018
• MRes (Distinction) Musculoskeletal Ageing, The MRC – Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing (CIMA), The University of Sheffield, Newcastle University and University of Liverpool, 2014
• BSc (Hons) Biomedical Science, The University of Sheffield, 2013

Memberships, editorial boards

• Grant review panel member/NC3Rs National Centre for the Replacement Refinement & Reduction of Animals in Research
• Fellow of the Higher Education Academy (FHEA)
• Editorial board/Frontiers in Endocrinology, Bone Research
• Member/American Society for Bone and Mineral Research (ASBMR), Washington, USA
• Member/British Orthopaedic Research Society (BORS): London, GB
• Member/Bone Research Society (BRS): Peterborough, GB
• Member/Osteoarthritis Research Society International (OARSI): Mount Laurel, NJ, US
• Member/The European Calcified Tissue Society (ECTS): Brussels, BE

Selected recent publications

Samvelyan, H. J., Huesa, C., Cui Lin, L., Farquharson, C., Staines, K. A. (2022) 'The role of accelerated growth plate fusion in the absence of SOCS2 on osteoarthritis vulnerability', Bone and Joint Research. Available at: https://doi.org/10.1302/2046-3758.113.BJR-2021-0259.R1

Coveney, C. R., Samvelyan, H. J., Miotla-Zarebska, J., Carnegie, J, Chang, E., Corrin, C. J., Coveney, T., Stott, B., Parisi, I., Duarte, C., Vincent, T. L., Staines, K. A. and Wann A. K. T. (2022) 'Ciliary IFT88 safeguards coordinated epiphyseal closure from disruptive physiological mechanical forces', Journal of Bone and Mineral research, 37(6), pp. 1081-1096. Available at: https://doi.org/10.1002/jbmr.4502

Samvelyan, H. J., Madi, K., Tornqvist, A. E., Javaheri, B. and Staines, K. A. (2021) 'Characterisation of growth plate dynamics in murine models of osteoarthritis', Frontiers in Endocrinology Bone Research. Available at: https://doi.org/10.3389/fendo.2021.734988

Samvelyan, H. J., Mathers, J. C. and Skerry, T. M. (2021) 'Fasting intervention potentiates the effect of mechanical loading to induce new bone formation in mice', The FASEB Journal. Available at: https://doi.org/10.1096/fj.202100334RR

Samvelyan, H., Hughes, D., Stevens, C. and Staines, K. A. (2020) 'Models of osteoarthritis: relevance and new insights', Calcified Tissue International. Available at: https://doi.org/10.1007/s00223-020-00670-x

Staines, K. A., Hardy, R. J., Samvelyan, H. J., Ward, K. and Cooper, R. (2020) 'Life course longitudinal growth and risk of knee osteoarthritis at age 53 years: evidence from the 1946 British birth cohort study', Osteoarthritis and Cartilage. Available at: https://doi.org/10.1016/j.joca.2020.12.012

Recent presentations and conferences

2023 Invited speaker, Karolinska Institutet Bone Hub Research Conference, Stockholm, Sweden.

2023 Invited speaker, Medical Research Council – Versus Arthritis Centre for Integrated Research Into Musculoskeletal Ageing (CIMA) and Centre for Musculoskeletal Ageing Research (CMAR) meeting, University of Birmingham, UK.

2023 Co-organiser, Chair and Speaker, School of Medicine Research Day, Chelmsford, UK.

2023 Invited speaker, Sport, Health and Performance Enhancement (SHAPE) Research Seminar, Nottingham Trent University, UK.

2022 Co-organiser and speaker, Medical Technology Research Centre Inaugural Annual Conference, Chelmsford, UK.

2022 Chair and Speaker, Bone Research Society Annual Meeting, Manchester, UK.

2022 Chair and Speaker, 49th European Calcified Tissue Society Congress, Helsinki, Finland.

2021 Speaker, Osteoarthritis Research Society International Virtual World Congress.

2019 Invited speaker, British Orthopaedic Research Society – Bone Research Society 5th Joint Conference, Cardiff, Wales. Awarded New Investigator Award.

2018 Invited speaker, European Cooperation In Science and Technology (eCOST) Action, Rome, Italy.

Media experience

Dr Samvelyan’s work in Musculoskeletal Ageing featured in:

• Cambridge Festival 2022, Cambridge
• British Science Festival 2021, Chelmsford
• Edinburgh Science Festival
• HubLE International Federation of Musculoskeletal Research Society (IFMRS) learning environment
• Orthopaedic Research Society (ORS) Education Online