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Pharmaceutical Science MSc

Chelmsford

Year 1

Advanced Pharmaceutics

You’ll be taught by specialists in drug delivery while you gain knowledge and practical skills to critically assess the design, formulation process and use of formulation of solid, semi-solid and liquid dosage. You’ll get hands-on when you investigate pharmaceutics-related problems to generate new data. In addition to the traditional dosage drug dosage forms, you’ll investigate advanced drug delivery approaches and systems such as vesicular carriers, dendrimers, solid lipid nanoparticles, carbon nanotubes, nanoemulsions and microspheres. You’ll also cover the use of biodegradable polymers in various drug delivery applications. While developing your understanding of physicochemical interactions and incompatibilities, you’ll become confident in practical decision making for effective medicine, the development of appropriate analytical techniques to assess dosage form stability and drug release profile.

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Drug Design and Discovery

Focus on the development pathway of a drug from its initial discovery to extensive clinical trials and regulatory approval. You’ll gain in-depth knowledge of the processes of finding a new target causing the disease, applying virtual and experimental models for compound/drug screening, identifying leading drug candidate for further development and performing pre-clinical research activities. You’ll cover the pre-formulation aspects of pharmaceuticals such as pH solubility and stability profiles, partition coefficients, determination of pKa, polymorphism, and compatibility studies of active ingredients and excipients. You’ll discuss the principles of instrumental chemical analysis of drugs and develop awareness of Good Laboratory Practice (GLP).This will ensure that you are establishing proper quality systems and ethical considerations, while constantly comparing to real-life industry examples.

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Postgraduate Research Design

Designed to give you the tools you need in order to identify and plan research to address a real world problem within your practice, or address a gap in the existing knowledge within your field. It’s designed for participants from across the Faculty which is reflected in the diverse content including: evaluating literature, designing research questions, systematic review procedures, qualitative and quantitative research methods and data analysis, issues of rigour and ethical considerations in research. We’ll provide a framework for you to propose and justify a research question and design appropriate to your professional practice.

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Pharmaceutical Manufacturing and Quality Principles

Develop wider knowledge of the integral parts of the pharmaceutical industry including research, development, manufacturing, distribution, marketing and sales. You’ll cover the considerations needed to plan, design, construct, validate, and operate complex manufacturing facilities. You’ll also study and debate the practical applications of Good Design Practices (GDPs) including compliance with applicable safety, health, environmental regulations and current Good Manufacturing Practice (cGMP). You’ll attend seminars which are delivered by pharmaceutical industry practitioners on issues in principles of quality assurance (QA) and quality control tests (QC), as well as understanding documentation, audit and test procedures you’ll need in your career. Finally, you’ll gain the knowledge and skills to apply Pharmaceutical Quality by Design (QbD) bases on the application of product and process sciences to provide accelerated regulatory submission pathways for new applications.

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Major Project

The major project is at the centre of the Masters award and allows you to demonstrate your creativity and apply the skills and concepts you have learned in the previous modules. It is the opportunity for you to carry out an in depth study in a specific area and to expand or redefine existing knowledge. In practical terms, you’ll be provided with a list of available research projects prior to the major project but will also have the opportunity to suggest your own projects. It is hoped that many of these projects will be carried out with either an industrial partner or a clinician. In the course of the project you may generate intellectual property, defined as an idea, invention or creation which can be protected by law from being copied by someone else.

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